University of Chicago

Decoding the Human
Microbiome

Our lab pioneers cutting-edge computational approaches to map the intricate networks connecting human biology with our microbial ecosystems.

By integrating genomics, deep learning, and systems biology, our research reveals fundamental principles of host-microbiome crosstalk that shape human health, disease susceptibility, and evolutionary adaptation.

University of Chicago
Blekhman Lab
Chicago skyline

Key Recent Publications

Upcoming Presentations

Apr
20–23

Translational Science 2026

Milwaukee, WI — Lauren Gonsalves

Apr
21

Janet D. Rowley Research Day

University of Chicago, Chicago, IL — Tess Brunner

Apr
22

University of Illinois

Chicago, IL — Ran Blekhman

May
2–5

Digestive Disease Week

Chicago, IL — Ran Blekhman, Lauren Gonsalves

May
10–12

Cell Symposia: Host-Microbiome Dynamics

Bruges, Belgium — Liz Gibbons

Jun
7–10

ASM Microbe

Washington, DC — JJ Colgan

Oct
27–31

Microbiome Conference

Cold Spring Harbor Labs, NY — Pamela Ferretti

Lab News

Human Microbiome Compendium

The Human Microbiome Compendium

An ongoing project to build a dataset of the human microbiome at an unprecedented scale.

Our Work in the Media